Transcriptomics

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Transcriptomic analysis of tumor-infiltrating dendritic cells in mouse subcutaneous tumor models


ABSTRACT: CCR7+ tumor-infiltrating DCs (tDCs) transport tumor antigens from the tumor to the draining lymph node (dLN), and thus play a pivotal role in anti-tumor CD8+ T cell responses. However, the molecular mechanisms that underlie tDC activity remain poorly understood. To elucidate this problem, we investigated the transcriptomic properties of CCR7+ tDCs in mouse subcutaneous tumor models.

ORGANISM(S): Mus musculus

PROVIDER: GSE110959 | GEO | 2020/02/21

REPOSITORIES: GEO

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