Transcriptomics

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Genome-wide transcriptional analysis of human patterned induced neurons (hpiNs)


ABSTRACT: We report that combining NGN2 programming with SMAD and WNT inhibition generates patterned induced neurons (hpiNs).Transcriptional analyses showed that hpiN cultures contained cells along a developmental continuumranging from poorly differentiated neuronal progenitors to well-differentiated, excitatory glutamatergic neurons. The most differentiated neurons could be identified using a CAMK2A::GFP reporter gene.

ORGANISM(S): Homo sapiens

PROVIDER: GSE112732 | GEO | 2018/04/24

REPOSITORIES: GEO

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