Transcriptomics

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Transcriptional profiling of Tmprss6-deficient mouse liver


ABSTRACT: Matriptase-2 (Tmprss6), a recently described member of the TTSP family, is an essential regulator of iron homeostasis. Tmprss6-/- mice display an overt phenotype of alopecia and a severe iron deficiency anemia. These hematological alterations found in Tmprss6-/- mice are accompanied by a marked up-regulation of hepcidin, a negative regulator of iron export into plasma.

ORGANISM(S): Mus musculus

PROVIDER: GSE11632 | GEO | 2008/06/04

SECONDARY ACCESSION(S): PRJNA106151

REPOSITORIES: GEO

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