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SW480 cells undergoes postmitotic neuron-like differentiation in response to EZH2 knockdown

ABSTRACT: Formerly we found that combined inhibition of class I HDACs, DNMTs, EZH2 and LSD1 with chemical inhibitors in a variety of cancer cells caused neuronal differentiation. Our recent study demonstrated that functional knockdown of EZH2 alone in SW480 cells can also lead to significant neuronal differentiation. We used microarray to analyze global gene expression change in SW480 cells after neuronal differentiation induced by EZH2 knockdown.

ORGANISM(S): Homo sapiens

PROVIDER: GSE118593 | GEO | 2018/12/31

REPOSITORIES: GEO

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SW480 cells undergoes postmitotic neuron-like differentiation in response to EZH2 knockdown

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