Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (Affymetrix HTA 2.0 data set)

ABSTRACT: We show that Glioma initiating cells (GICs) can, through MES transition, enter a reactive-astrocyte-like cell state which is connected to increased therapy resistance

ORGANISM(S): Homo sapiens

PROVIDER: GSE122807 | GEO | 2020/11/30

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (DNA methylation data set)

Project description:We show that Glioma initiating cells (GICs) can, through MES transition, enter a reactive-astrocyte-like cell state which is connected to increased therapy resistance

2020-11-30 | GSE122808 | GEO

Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (Affymetrix HTA 2.0 data set)

Project description:Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (Affymetrix HTA 2.0 data set)

| PRJNA506416 | ENA

Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity

Project description:Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity

| PRJNA506413 | ENA

Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity

Project description:This SuperSeries is composed of the SubSeries listed below.

2020-11-30 | GSE122809 | GEO

Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (DNA methylation data set)

Project description:Mesenchymal transition and acquired therapy resistance of glioblastoma cells is connected to astrocyte reactivity (DNA methylation data set)

| PRJNA506417 | ENA

Connected to Nature

Project description:Gut microbiota and serotonin alter after Connected to nature intervention

| PRJEB34058 | ENA

Exon Level Expression Profiling:HTA 2.0 array

Project description:Transcriptome analysis of RNA samples extracted from human placenta FFPE sample RNA expression level comparison

2022-03-14 | GSE198252 | GEO

Connected gene communities underlie transcriptional changes in Cornelia de Lange Syndrome

Project description:Cornelia de Lange syndrome (CdLS) is a complex multisystem developmental disorder caused by mutations in cohesin subunits and regulators. While the precise molecular mechanisms are not well defined, they point toward a global deregulation of the transcriptional gene expression program. Indeed, cohesin is associated with the boundaries of chromosome domains in addition to enhancers and promoters connecting the 3D genome organization with transcriptional control and gene expression. Here we show that connected gene communities, built with noncoding regulatory elements and genes physically interacting in the 3D chromosomal space, provide a molecular explanation for the pathoetiology of CdLS. Indeed, NIPBL and cohesin are important constituents of connected gene communities, both being centrally positioned at active noncoding regulatory elements. Interestingly, mutations in SMC1A and NIPBL lead to coordinated gene expression changes in connected communities. Our findings suggest a model where CdLS is explained by coordinated modulation of connected gene communities.

2017-07-13 | GSE93080 | GEO

Glacial microbiota are hydrologically connected and temporarily variable.

Project description:Glacial microbiota are hydrologically connected and temporarily variable.

| PRJEB36007 | ENA

Exon Level Expression Profiling:HTA 2.0 array

Project description:Exon Level Expression Profiling:HTA 2.0 array

| PRJNA814287 | ENA