Transcriptomics

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Expression data from Ricin-A expressing Drosophila wing discs


ABSTRACT: Coordinated tissue growth is essential for generation of functionally integrated organs during animal development as well as for tissue homeostasis during adult life. Using Drosophila wing as a model system we have demonstrated that impairing growth, by expression of a cold sensitive version of type 2 ribosome-inactivating protein Ricin-A (RA), within defined territories along the wing primordium triggers a Dmp53-dependent reduction of growth in adjacent non-perturbed cells. To identify novel genes and pathways involved in coordinating intra-organ growth we analysed differential gene expression between wing discs expressing RA and control wing discs expressing GFP in the posterior compartment by using engrailed-Gal4.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE125794 | GEO | 2019/07/01

REPOSITORIES: GEO

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