Genomics

Dataset Information

0

CRISPR screening reveals targets to reprogram long-lived effector CD8+ T cells for cancer therapy. [ATAC-Seq]


ABSTRACT: CD8+ T cells can be reprogrammed for better persistence and robust effector function in TME. By performing an in vivo pooled CRISPR-Cas9 mutagenesis screening of metabolism-associated factors, we identify Regnase-1 as a major negative regulator of antitumor responses, whose deficiency results in drastically increased CD8+ T cell accumulation in tumors

ORGANISM(S): Mus musculus

PROVIDER: GSE126070 | GEO | 2019/12/11

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-12-11 | GSE137015 | GEO
2019-12-11 | GSE126071 | GEO
2019-12-11 | GSE137014 | GEO
2019-12-11 | GSE137016 | GEO
2021-04-07 | GSE155020 | GEO
2020-01-09 | GSE118110 | GEO
2021-07-21 | GSE171442 | GEO
2017-12-16 | GSE107150 | GEO
2024-09-23 | GSE274735 | GEO
2019-12-11 | GSE126072 | GEO