Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Functional characterization of the Differences Between Parotid and Submandibular Salivary Glands

ABSTRACT: We applied both single cell and bulk RNA-sequencing to characterize and identify uniqueness in gene expression of the mouse Parotid gland compared to other tissues including the submandibular gland

ORGANISM(S): Mus musculus

PROVIDER: GSE131285 | GEO | 2019/10/07

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Functional characterization of the Differences Between Parotid and Submandibular Salivary Glands

Project description:Functional characterization of the Differences Between Parotid and Submandibular Salivary Glands

| PRJNA543115 | ENA

Adult parotid gland RNA-seq libraries, and embryonic submandibular gland RNA-seq libraries

Project description:Adult parotid gland RNA-seq libraries and embryonic submandibular gland RNA-seq libraries were created to examine the mRNA species present in these secretory glands, as part of a project to understand acinar glands in general.

2017-08-18 | GSE102788 | GEO

Male/Female BALB/c Mouse Submandibular/Sublingual/Parotid/Lacrimal/Meibomian Glands

Project description:Series includes pooled (n = 5 mice per biological replicate) samples from submandibular, sublingual, parotid, lacrimal, and meibomian glands of BALB/c mice. Both male and female samples were analyzed on CodeLink Mouse Uniset I Microarrays. Keywords: repeat sample

2004-11-24 | GSE1503 | GEO

Three Major salivary glands

Project description:The aim of this study is characterize the gene expression of rat parotid, submandibular and sublingual glands, providing basic information for the salivary marker proteins.

2010-05-15 | GSE21843 | GEO

Transcription profiling by array of submandibular salivary glands from PAP knockout and wild type mice

Project description:Prostatic acid phosphatase is the main acid phosphatase in mouse submandibular salivary gland

2014-04-15 | E-MTAB-2099 | biostudies-arrayexpress

Gene expression data from AKT induced salivary gland tumors

Project description:Rapamycin treatment of AKT induced salivary gland tumors Normal tissue (parotid and submandibular), untreated tumor tissue, and tumor tissue treated for 3/14 days

2013-01-14 | E-GEOD-23435 | biostudies-arrayexpress

Molecular Characterization of the Human and Mouse Parotid Gland

Project description:Gene expression of 4 human parotid gland samples were comapred with 4 mouse parotid gland samples. Keywords: Comparative Gene Expression

2007-08-13 | GSE6017 | GEO

Salivary Gland Tissue Recombination Can Modify Cell Fate [scRNA-seq]

Project description:Although mesenchyme is essential for inducing the epithelium of ectodermal organs, its precise role in organ-specific epithelial fate determination remains poorly understood. To elucidate roles of tissue interactions in cellular differentiation, we performed single cell RNA sequencing and imaging analyses of recombined tissues in which embryonic mouse salivary gland mesenchyme and epithelium were switched ex vivo. We found partial induction of molecules that define gland-specific acinar and myoepithelial cells in recombined salivary epithelium. Parotid epithelium (serous gland) recombined with submandibular mesenchyme (mixed serous-mucous, but predominantly mucous gland) began to express mucous acinar genes not intrinsic to the parotid gland. While myoepithelial cells do not normally line parotid acini, newly induced myoepithelial cells densely populated recombined parotid acini. However, mucous acinar and myoepithelial markers continued to be expressed in submandibular epithelial cells recombined with parotid mesenchyme. Consequently, some epithelial cells appeared to be plastic, such that their fate could still be altered in response to mesenchymal signaling, whereas other epithelial cells appeared to be already committed to a specific fate. We also discovered evidence for bidirectional induction: transcriptional changes were observed not only in the epithelium but also in the mesenchyme after heterotypic tissue recombination. For example, parotid epithelium induced the expression of muscle-related genes in submandibular fibroblasts that began to mimic parotid fibroblast gene expression. These studies provide the first comprehensive unbiased molecular characterization of tissue recombination approaches exploring the regulation of cell fate.

2024-05-15 | GSE247700 | GEO

Salivary Gland Tissue Recombination Can Modify Cell Fate [bulk RNA-seq]

2024-05-15 | GSE247699 | GEO

Molecular Characterization of the Human and Mouse Parotid Gland

Project description:Gene expression of 4 human parotid gland samples were comapred with 4 mouse parotid gland samples. Human and mouse parotid gland gene expression was screened using custom-designed targeted cDNA containing probes for 198 genes which encode for ion/water transporter (75 genes) and receptor/regulatory (101 genes) proteins potentially involved in the fluid secretion mechanism, as well as 11 secretory protein genes and 11 control genes

2007-08-13 | E-GEOD-6017 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data