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Meg-3 meg-4 mutants are defective in exogenous RNAi signal amplification

ABSTRACT: Worms were fed a dsRNA trigger against the pos-1 gene and subjected to sRNAseq to see if they could amplify the exogenous RNAi trigger. meg-3 meg-4 were not able to amplify the signal as robustly as wild-type.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE134627 | GEO | 2019/07/23

REPOSITORIES: GEO

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meg-3 meg-4 mutants are defective in exogenous RNAi signal amplification

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