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Biphasic response of Protein Kinase A to cyclic adenosine monophosphate triggers distinct epithelial phenotypes

ABSTRACT: We postulated that the ability of bPAC-generated cAMP to induce the biphasic response of PKA might have profound and distinct effects on the cellular transcriptome. To test this hypothesis, we carried out mRNA sequencing of MDCKI and MDCKI+bPAC cells under no, low, or high cAMP inputs (0%, 1.7% and 33% blue light duty cycle)

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE134650 | GEO | 2019/12/31

REPOSITORIES: GEO

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Gene expression in undifferentiated or cyclic adenosine monophosphate-exposed BeWo trophoblast cells

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Biphasic response of Protein Kinase A to cyclic adenosine monophosphate triggers distinct epithelial phenotypes

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Diverse effects of cyclic AMP variants on osteogenic and adipogenic differentiation of human mesenchymal stromal cells

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