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Genetic studies of MYC in prostate cancer cell lines

ABSTRACT: In order to dissect the contribution of MYC to prostate cancer development, we overexpressed MYC in RWPE-1 cells and knocked down MYC in LNCaP cells. We performed RNA-seq on those cells. In the LNCaP cells only, we also performed ChIP-seq against MYC, H3K27ac, H3K27me3, and RNAP2.

ORGANISM(S): Homo sapiens

PROVIDER: GSE135942 | GEO | 2020/06/30

REPOSITORIES: GEO

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