Transcriptomics

Dataset Information

0

CSF-1 induced gene expression in human whole blood


ABSTRACT: CSF-1 is a key regulator of the macrophage lineage. Macrophages are key mediators of inflammation, cancer, and homeostasis and in some cases differentiate from infiltrating blood monocytes. To better understand the the impact of CSF-1 on blood monocytes, transcriptomic changes in ex vivo cultured human whole blood were measured 4 and 24 hrs after addition of CSF-1 and compared to blood cultured without adding CSF-1. The expression of more than 50 genes was induced with geometric means >2-fold relative to unstimulated control conditions (p<0.05) at either 4 or 24 hrs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE136440 | GEO | 2019/08/28

REPOSITORIES: GEO

Similar Datasets

2012-05-20 | E-GEOD-37029 | biostudies-arrayexpress
2014-11-27 | E-GEOD-63662 | biostudies-arrayexpress
2012-04-12 | E-GEOD-27792 | biostudies-arrayexpress
2015-04-21 | E-GEOD-68061 | biostudies-arrayexpress
2020-12-09 | GSE155719 | GEO
2015-05-22 | GSE46734 | GEO
2019-05-09 | GSE130881 | GEO
2015-04-01 | E-GEOD-65670 | biostudies-arrayexpress
2024-01-01 | E-MTAB-5752 | biostudies-arrayexpress
2023-07-14 | GSE156696 | GEO