Neutrophil-derived microvesicle induced dysfunction of the blood-brain barrier in vitro
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ABSTRACT: The aim of this study is to understand how NMV can affect the vascular integrity of the blood-brain barrier using a cell line- hCMEC/D3. Recent studies have reported that NMV can affect other endothelial barriers in the body contributing to inflammation and pathogenesis of diseases such as atherosclerosis. The transcriptomic profile of NMV-treated hCMEC/D3 cells was compared to that of cells without treatment to understand whether functional groupings and pathways are differentially expressed, which can contribute to changes in blood-brain barrier.
ORGANISM(S): Homo sapiens
PROVIDER: GSE137111 | GEO | 2019/12/05
REPOSITORIES: GEO
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