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RNA-seq analysis of Ehrlichia muris infection induced murine splenic and hepatic memory B cells subsets.

ABSTRACT: Purpose: The goal of this study is to complare the transcitpional profiles of freshly isolated, murine splenic and hepatic memory B cells (B220+ CD73+) sorted as CD11b, CD11c double negative and CD11b, CD11c double positive cell populations induced by Ehrlichia muris infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE137154 | GEO | 2019/09/10

REPOSITORIES: GEO

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Ehrlichia muris

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Transcriptional analysis of murine CXCR3+ vs. CXCR3- peritoneal cavity B cells 8 days following infection with Ehrlichia muris.

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A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation

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Microarray analysis of Zbtb46 KO CD4+ splenic DCs and bone marrow erythroid progenitors

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Trichuris muris transcriptomics

Project description:Trichuris muris is very closely related to the human parasite T. trichiura sharing cross reactive antigens. Moreover, it is a remarkably tractable model system for dissecting immune responses and host parasite relationships and is actively being investigated in a number of laboratories worldwide. T. muris is a naturally occurring nematode parasite of mice which resides in the caecum and colon and has a direct oral faecal life cycle. High-throughput sequencing of Trichuris muris transcriptome for de novo assembly of transcripts. The main objective of this project is to recognize genes expressed in given life stages. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

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