Transcriptomics

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Microarray analysis of the development of proteinuria in the Dahl salt-sensitive rat


ABSTRACT: To get more insight in cause and consequences of proteinuria, we studied glomerular gene expression patterns before and after the onset of increased urinary albumin excretion in a proteinuric rat strain. Spontaneously proteinuric Dahl salt-sensitive rats (Dahl SS) were compared to non-proteinuric, spontaneously hypertensive rats (SHR). In Dahl SS, UAE significantly increased starting from week 5 of age. Glomerular RNA profiles of 4- and 6 week-old rats were studied by Affymetrix microarrays. Keywords: Time course analysis

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE13810 | GEO | 2009/01/01

SECONDARY ACCESSION(S): PRJNA110581

REPOSITORIES: GEO

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