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ENO1-IT1(ENSG00000236269.1) coordinates the acetylation of histone genome-wide in Colorectal Cancer

ABSTRACT: LncRNA ENO1-IT1 has been found to be mainly located in the nucleus of colorectal mucosa epithelial cells, which indicates that this lncRNA may be responsible for regulating the expression of target gene. To address whether ENO1-IT1 modulates epigenetic changes genome-wide, we performed chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq) in HCT116 cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE139403 | GEO | 2022/10/25

REPOSITORIES: GEO

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mRNA expression of colorectal cancer cell line HCT116 transfected with lncRNA-SPRY4-IT1 overexpression or control vector

Project description:To determine the mRNA expression profile of colorectal cancer cell line HCT116 transfected with lncRNA-SPRY4-IT1 overexpression vector, we performedd gene expression microArray analysis to examine the expression of mRNAs.

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ENO1-IT1(ENSG00000236269.1) coordinates the acetylation of histone genome-wide in Colorectal Cancer

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The long noncoding RNA SPRY4-IT1 increases the proliferation of human breast cancer cells by upregulating ZNF703 expression

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