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The effect of beta-glucan - induced trained immunity on the transcriptomic profile of tumor-associated monocytes

ABSTRACT: Induction of trained immunity by beta-glucan has been shown to promote transcriptomic alterations in myeloid cells. Monocytes are involved in the immune responses against tumors. In this study, we performed RNA sequencing in tumor-infiltrated monocytes from mice in order to investigate the impact of trained immunity on the transcriptomic profile of monocytes in the tumor setting.

ORGANISM(S): Mus musculus

PROVIDER: GSE139451 | GEO | 2020/10/30

REPOSITORIES: GEO

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