Transcriptomics

Dataset Information

0

Gene expression analysis of delg_mut versus Df_plus control


ABSTRACT: Nuclear transcription factors drive mitochondrial mass by regulating the expression of genes encoding mitochondrial proteins. Among these factors, nuclear respiratory factor 2 (NRF-2/GABP) has been proposed to be critical for mitochondrial mass in mammalian cells, yet there is little genetic evidence to support this function in vivo. Here, we show that mutants of the Drosophila melanogaster NRF-2alpha/GABPalpha homologue Delg (CG6338) have reduced expression of multiple genes encoding mitochondrial proteins, leading to reduced mitochondrial mass.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE14058 | GEO | 2009/02/09

SECONDARY ACCESSION(S): PRJNA112423

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2009-02-21 | E-GEOD-14058 | biostudies-arrayexpress
2021-02-01 | GSE145089 | GEO
2007-06-28 | E-CBIL-28 | biostudies-arrayexpress
2009-07-15 | GSE16067 | GEO
2010-04-27 | E-GEOD-21340 | biostudies-arrayexpress
2010-04-14 | GSE21340 | GEO
2009-07-15 | E-GEOD-16067 | biostudies-arrayexpress
2008-09-03 | GSE12643 | GEO
2023-05-22 | GSE99138 | GEO
2023-05-22 | GSE99137 | GEO