Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

A Novel Progesterone Biosensor Derived from Microbial Screening

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Pimelobacter simplex

PROVIDER: GSE141604 | GEO | 2020/03/09

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

A Novel Progesterone Biosensor Derived from Microbial Screening [ChIP-seq]

Project description:Determination of target binding sites of a novel allosteric transcription factor, SRTF1

2020-03-10 | GSE131041 | GEO

A Novel Progesterone Biosensor Derived from Microbial Screening [RNA-seq]

Project description:Mining of gene clusters responsive to hormones

2020-03-10 | GSE141603 | GEO

A progesterone biosensor derived from microbial screening.

Project description:Bacteria are an enormous and largely untapped reservoir of biosensing proteins. We describe an approach to identify and isolate bacterial allosteric transcription factors (aTFs) that recognize a target analyte and to develop these TFs into biosensor devices. Our approach utilizes a combination of genomic screens and functional assays to identify and isolate biosensing TFs, and a quantum-dot Förster Resonance Energy Transfer (FRET) strategy for transducing analyte recognition into real-time quantitative measurements. We use this approach to identify a progesterone-sensing bacterial aTF and to develop this TF into an optical sensor for progesterone. The sensor detects progesterone in artificial urine with sufficient sensitivity and specificity for clinical use, while being compatible with an inexpensive and portable electronic reader for point-of-care applications. Our results provide proof-of-concept for a paradigm of microbially-derived biosensors adaptable to inexpensive, real-time sensor devices.

| S-EPMC7062782 | biostudies-literature

A Novel Progesterone Biosensor Derived from Microbial Screening

Project description:A Novel Progesterone Biosensor Derived from Microbial Screening

| PRJNA594030 | ENA

A Novel Progesterone Biosensor Derived from Microbial Screening [RNA-seq]

Project description:A Novel Progesterone Biosensor Derived from Microbial Screening [RNA-seq]

| PRJNA594032 | ENA

A Novel Progesterone Biosensor Derived from Microbial Screening [ChIP-seq]

Project description:A Novel Progesterone Biosensor Derived from Microbial Screening [ChIP-seq]

| PRJNA542377 | ENA

Urban waterways microbial communities

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-12-21 | E-GEOD-64376 | biostudies-arrayexpress

Progesterone Receptor Targetome in the Mammary Gland

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-08-27 | E-GEOD-42888 | biostudies-arrayexpress

Protein Array Screening of Myelodysplastic Syndromes

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-11-21 | E-GEOD-48155 | biostudies-arrayexpress

microRNA screening in human pancreatic adenocarcinoma

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-11-03 | E-GEOD-74574 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data