Transcriptomics

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Gene expression profile of primary cultures of neonatal cardiomyocytes treated with specific GapmeRs


ABSTRACT: The eRNAs are non coding transcripts involved in the control of gene expression. To verify the biological effects of IRENE-SS and -div (Intergenic Regulatory Element Nkx2-5 Enhancer -same strand and -divergent) knockdown, we analyzed the differentially gene expression profile of cells treated with either of the two specific gapmers versus cardiomyocytes transfected with a scrambled sequence control. We also determined whether IRENE-SS or -div silencing modified the expression of NKX2-5 target genes.

ORGANISM(S): Mus musculus

PROVIDER: GSE143929 | GEO | 2020/09/07

REPOSITORIES: GEO

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