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Transcriptomic profiling of drug-naïve or proteasome inhibitor-resistant myeloma cell lines

ABSTRACT: RNA was extracted from myeloma cell lines that were either drug-naïve or resistant to bortezomib or carfilzomib and the transcriptome was characterised using RNA sequencing.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE144249 | GEO | 2021/12/01

REPOSITORIES: GEO

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Secondary proteasome inhibitor carfilzomib resistant myeloma cell lines

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Transcriptomic profiling of drug-naïve or proteasome inhibitor-resistant myeloma cell lines

Project description:Transcriptomic profiling of drug-naïve or proteasome inhibitor-resistant myeloma cell lines

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The mitochondrial protease LonP1 promotes proteasome inhibitor resistance in multiple myeloma.

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