Transcriptomics

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Transcriptional dynamics of hepatic sinusoid-associated cells after liver injury [scRNA-seq]


ABSTRACT: Here we profile the transcripts of app. 35.000 single cells isolated from livers of healthy and diseased mice. We show the transcriptomic change associated with fibrosis induction in the non-parenchymal cell types (hepatic stellate cells, liver endothelial cells and macrophages). We reveal a hitherto unknown feature of the HSCs otherwise functionally attributed to the LECs.

ORGANISM(S): Mus musculus

PROVIDER: GSE145086 | GEO | 2020/08/25

REPOSITORIES: GEO

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