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Circular RNAs Expression in Elderly Patients with Postoperative Cognitive Dysfunction

ABSTRACT: Postoperative cognitive dysfunction (POCD) is one of the severe complications inducing low life quality and high mortality after surgery, especially in elderly patients.Here we probed differentially expressed circRNAs using microarray assay in POCD patients, aiming to find potential key circRNAs related to the occurrence of POCD. Subsequently, ten dysregulated circRNAs were confirmed via quantitative real-time polymerase chain reaction (qRT-PCR) in 10 paired samples. Then, Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to probe the vital functions of dysregulated genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE147277 | GEO | 2020/07/14

REPOSITORIES: GEO

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