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Transcriptomic Comparison of Common Nontyphoidal Salmonella Serovars Provides Greater Resolution for Understanding Differences in Virulence

ABSTRACT: RNA extracted from representative isolates of each serovar grown to late exponential phase in Luria-Bertani broth showed that transcript abundances of core genes were significantly higher (p < 0.05) than those of accessory genes for all three serovars. Inter-serovar comparisons demonstrated higher transcript abundances for genes related to vitamin B12 biosynthesis, and ethanolamine and 1,2-propanediol utilization in S. Cerro compared to Javiana and Typhimurium, while genes in Salmonella Pathogenicity Island (SPI) 1 had significantly higher transcript abundances in S. Javiana and S. Typhimurium.

ORGANISM(S): Salmonella enterica subsp. enterica serovar Javiana Salmonella enterica subsp. enterica serovar Typhimurium Salmonella enterica subsp. enterica serovar Cerro

PROVIDER: GSE150943 | GEO | 2020/05/21

REPOSITORIES: GEO

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