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Gene expression analysis of the apical portion of pterygium and control conjunctiva tissues to screen the comprehensive gene expression levels

ABSTRACT: A sight threatening, pterygium is a common ocular surface disorders identified by fibrovascular growth of the cornea and induced by variety of stress factors, like ultraviolet (UV) exposure. However, the genes involved in the etiopathogenesis of this disease is not well studied.

ORGANISM(S): Homo sapiens

PROVIDER: GSE151872 | GEO | 2020/08/31

REPOSITORIES: GEO

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Expression profiling explores pathways involved in pterygium progression

Project description:Pterygium is an ocular surface disease that can cause visual impairment if it progressively invades the cornea. Although many pieces of research showed that ultraviolet radiation triggers pterygium pathological progress, the underlying mechanism in pterygium remains indistinct. In this study, we used microarray to evaluate the changes of transcripts between primary pterygium and adjacent normal conjunctiva samples in China, hoping to find underlying pathways involved in pterygium progression.

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