Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from PTC cell lines transfected with FAM60A-shRNA

ABSTRACT: The mRNA and protein levels of FAM60A were significantly upregulated in PTC cancer tissues compared with paired normal tissue. Knockdown of FAM60A1 in TPC-1 and K1 significantly supressed cell growth, colony formation ability, tumor invasion, and phase transition of the cell cycle. We used microarrays to investigate the gene expression alterations of PTC cells after FAM60A knockdown by shRNA.

ORGANISM(S): Homo sapiens

PROVIDER: GSE154331 | GEO | 2020/11/26

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Expression data from PTC cell lines transfected with SHCBP1-shRNA

Project description:The mRNA and protein levels of SHCBP1 were significantly upregulated in PTC cancer tissues compared with paired normal tissue. Knockdown of SHCBP11 in TPC-1 and K1 significantly supressed cell growth, colony formation ability, tumor invasion, and phase transition of the cell cycle. We used microarrays to investigate the gene expression alterations of PTC cells after SHCBP1 knockdown by shRNA.

2020-10-04 | GSE154307 | GEO

Expression data from PTC cell lines transfected with FAM60A-shRNA

Project description:Expression data from PTC cell lines transfected with FAM60A-shRNA

| PRJNA645900 | ENA

Identification of target genes of miR-31 in PTC cells by RNA sequencing

Project description:The purposes of this study were to compare and analyze the expression differences of papillary thyroid carcinoma (PTC) induced by BrafV600E after knockdown of miR-31 deletion. And in order to gain insights into global gene expression regulated by miR-31 in human PTC cells, RNA-Seq experiments were performed in K1 cells with knockdout of miR-31.

2022-03-31 | GSE193159 | GEO

Identification of transcriptional targets of TBX3 in PTC cells and mPTC by RNA sequencing

Project description:The purposes of this study were to compare and analyze the expression differences of mouse papillary thyroid carcinoma (mPTC) induced by BrafV600E after Tbx3 deletion. And in order to gain insights into global gene expression regulated by TBX3 in human PTC cells, RNA-Seq experiments were performed in K1 cells with knockdown of TBX3.

2021-04-30 | GSE166513 | GEO

MeRIP-seq of K1 PTC cells

Project description:MeRIP-seq of K1 PTC cells

| PRJNA750468 | ENA

Expression data from PTC cell lines transfected with SHCBP1-shRNA

Project description:Expression data from PTC cell lines transfected with SHCBP1-shRNA

| PRJNA645835 | ENA

Next Generation Sequencing of transfected NC K1 cells and transfected si-NEAT1_2 K1 cells

Project description:Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of transfected NC K1 cells and transfected si-NEAT1_2 K1 cells. The goals of this study are to analysis the different mRNA expression between transfected NC K1 cells and transfected si-NEAT1_2 K1 cells. Quantitative reverse transcription polymerase chain reaction (qRT–PCR) methods and to evaluate protocols for optimal high-throughput data analysis. We performed mRNA-seq in the NEAT1_2 knockdown group and NC group in the K1 cell line. We found that after knockdown of NEAT1_2, 615 mRNAs were upregulated and 2364 mRNAs were downregulated.

2020-12-05 | GSE159905 | GEO

Differentially expression profiling in Hashimoto's thyroiditis (HT), papillary thyroid carcinoma (PTC) with HT in background, PTC without HT in background, micro PTC (mPTC), and three normal thyroid samples (TN).

Project description:Experiment: Establishment of expression profiles in HT, PTC with HT, PTC without HT, and mPTC in comparison to TN samples. TN samples were downloaded as CEL files from the repository of the microarray vendor. Biostatistical analysis focussed in first instance on identifying genes and biofunctions related to HT and PTC with HT.

2020-06-16 | GSE138198 | GEO

BLU667-adapted transcriptome in CCDC6-RET fusion papillary thyroid carcinoma (TPC) cells

Project description:To investigate the short-termed and long-termed transcriptomic changes induced by the RET tyrosine kinase inhibitor BLU667 in TPC-1 human PTC cells

2023-04-11 | GSE211371 | GEO

R-protein composition of budding yeast PTC deficient 80S ribosomes

Project description:Ribosomal RNA modifications are introduced during ribosome assembly by snoRNA and stand-alone modification enzyme based mechanisms in budding yeast. Lack of individual modifications in rRNA has a minor effect on yeast growth, ribosome biogenesis, and translation, which has complicated the definition of the biological function of rRNA modifications. We have constructed a S.cerevisiae strain lacking 7 25S rRNA modifications (Ψ2826, Um2921, Gm2619, m5C2870, Ψ2880, Um2724 and Gm2922)in peptidyl-transferase center. This strain exhibits severely compromised growth at 30°C, reduced level of global translation and actively translating ribosomes and cold sensitivity. Ribosomal protein composition of the mature 80S ribosomes was analyzed by SILAC based qMS approach. We have found that absence of PTC modifications around PTC does not affect significantly r-protein content of 80S ribosomes.

2024-06-23 | PXD051211 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data