Reduced Physical Activity Alters the Leucine-Stimulated Translatome in Aged Skeletal Muscle
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ABSTRACT: Background: Periods of inactivity experienced by older adults induce nutrient anabolic resistance creating a cascade of skeletal muscle transcriptional and translational aberrations contributing to muscle dysfunction. Objective: To identify how inactivity alters leucine-stimulated translation of molecules and pathways within the skeletal muscle of older adults.
ORGANISM(S): Homo sapiens
PROVIDER: GSE162730 | GEO | 2020/12/06
REPOSITORIES: GEO
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