Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of ZNF676 KD Win1 naive embryonic stem cells and control cells

ABSTRACT: RNA-seq analysis of Win1 naive embryonic stem cells carrying an shRNA against ZNF676 and a control shRNA

ORGANISM(S): Homo sapiens

PROVIDER: GSE163544 | GEO | 2022/01/28

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA-seq of ZNF676 KD Win1 naive embryonic stem cells and control cells

Project description:RNA-seq of ZNF676 KD Win1 naive embryonic stem cells and control cells

| PRJNA686655 | ENA

ZNF676 ChIP-seq in HEK293T and H1 cells

Project description:Genome-wide binding profile of the primate-specific KRAB zinc finger protein ZNF676 in cell lines overexpressing the protein.

2022-01-28 | GSE163541 | GEO

ZNF676 and ZNF728 ChIP-exo in HEK293T cells

Project description:Genome-wide binding profile of the primate-specific KRAB zinc finger proteins ZNF676 and ZNF728 in cell lines overexpressing the proteins.

2022-01-28 | GSE163540 | GEO

RNA-seq of differentiated primary normal human bronchoepithelial (NHBE) cells overexpressing ZNF676.

Project description:RNA-seq of primary normal human bronchoepithelial (NHBE) cells differentiated to have cilia. They express either ZNF676 (experiment), either LacZ (control).

2022-01-28 | GSE163543 | GEO

ZNF676 ChIP-seq in HEK293T and H1 cells

Project description:ZNF676 ChIP-seq in HEK293T and H1 cells

| PRJNA686652 | ENA

ZNF676 and ZNF728 ChIP-exo in HEK293T cells

Project description:ZNF676 and ZNF728 ChIP-exo in HEK293T cells

| PRJNA686651 | ENA

Systematic Identification of Defined Conditions for Induction and Maintenance of Naive Human Pluripotency [expression]

Project description:Embryonic stem cells (ESCs) of mice and humans have distinct molecular and biological characteristics, raising the question whether an earlier ‘naive’ state of pluripotency may exist in humans. Here we took a systematic approach to identify small molecules that support autonomous self-renewal of naive human ESCs based on maintenance of endogenous OCT4 distal enhancer activity, a molecular signature of ground state pluripotency. Iterative chemical screening identified a combination of five kinase inhibitors that induces and maintains OCT4 distal enhancer activity when applied directly to conventional human ESCs. These inhibitors generate a homogeneous population of human pluripotent stem cells in which transcription factors associated with the ground state of pluripotency are highly upregulated. Comparison with previously reported naive human ESCs indicates that our kinase inhibitor cocktail captures a novel pluripotent state in humans that closely resembles mouse ESCs. Expression analysis was performed on two groups of human ESC samples: WIBR2 (P12 and P14), WIBR3 (P9) and WIN1 (P10) human ESCs derived in our optimized naive medium (5i/L/A or 6i/L/A, as indicated), and parental WIBR2 and WIBR3 human ESCs in primed human ESC medium.

2014-07-16 | E-GEOD-59430 | biostudies-arrayexpress

Transcriptional profiling of human naive embryonic stem cells

Project description:Transcriptional profiling of human naive embryonic stem cells

| PRJEB12748 | ENA

DNA methylation profiling of human naive embryonic stem cells

Project description:Human pluripotent cell lines were derived from blastocyst-stage embryos and propagated in self-renewal conditions that maintain features of naive pluripotency characteristic of mouse embryonic stem cells. Genome-wide DNA methylation status of HNES1 and HNES3 naive and primed cells was assessed with post-bisulfite adapter tagging (PBAT).

2016-03-01 | E-MTAB-4462 | biostudies-arrayexpress

BLUEPRINT EpiVar RNA-seq for Naive naive CD4+ T-cells

Project description:BLUEPRINT EpiVar RNA-seq for Naive naive CD4+ T-cells

| EGAS00001000752 | EGA