TLR7/8 Agonist Treatment Induces an Increase in Bone Marrow Resident Dendritic Cells and Hematopoietic Progenitor Expansion and Mobilization
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ABSTRACT: Treatment with the TLR7/8 agonist R848 results in a significant increase in classic dendritic cells (DCs) in the bone marrow, but a decrease in common dendritic cell progenitors and pre-DCs. Phenotypic analysis of DCs showed that R848 treatment is associated with altered expression of certain chemokines, activation markers, and migratory receptors.
ORGANISM(S): Mus musculus
PROVIDER: GSE163600 | GEO | 2021/02/01
REPOSITORIES: GEO
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