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Expression profiling by RNA-seq for identifying genes associated with prognosis in non-muscle-invasive bladder cancer.

ABSTRACT: Non-muscle-invasive bladder cancer (NMIBC) is clinically heterogeneous, and many NMIBC patients fail to respond to treatment and frequently experience disease relapse. We aim to identify a prognostic and predictive signature of the NMIBC heterogeneity. We constructed a transcriptomic data set by RNA-seq experiments from an independent NMIBC patient cohort (n=32). This cohort contains the patients stratified into three prognostic subgroups: Group 1 (patients with non-relapse; n=15), Group 2 (patients experiencing recurrence, n=9), and Group 3 (patients experiencing progression; n=8).

ORGANISM(S): Homo sapiens

PROVIDER: GSE163899 | GEO | 2021/02/16

REPOSITORIES: GEO

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Development of a prognostic index for predicting disease progression in non-muscle invasive bladder cancer

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