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Genome wide map of Runx3 bound regions in murine splenic CD8 T cells

ABSTRACT: Runx3 is an important transcription factor for the proper development of CD8+T cells. The number and functionality of CD8+T cells is severely affected in the absence of Runx3. To gain insight into the transcriptional program managed by Runx3 in CD8+T cells we conducted ChIP-seq on 50 million cells and CUT&RUN on 150,000 cells, using anti Runx3 antibodies. Both assays revealed similar results.

ORGANISM(S): Mus musculus

PROVIDER: GSE164536 | GEO | 2021/01/12

REPOSITORIES: GEO

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Genome-wide maps of Runx3 bound regions in splenic CD8+ T cells.

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