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RNA-seq analysis of Igf2's function in the differentiation of mouse embryonic stem cells

ABSTRACT: We report the function of IGF2 in regulating the differentiation of ESCs, and then we performed RNA-seq for the wild-type and Igf2 knockout ESCs and embryoid bodies collected at different time points to analyze the transcriptomes. The results showed a significant difference between wild-type and Igf2 knockout groups in transcriptomes, and we performed a series experiments to study the function of Igf2 in the differentiation of ESCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE173810 | GEO | 2021/07/09

REPOSITORIES: GEO

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