Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional changes in HK-2 cells treated with lysophosphatidylcholine (LPC)

ABSTRACT: To confirm gene expression changes upon LPC stimulation of HK-2 cells, we performed microarray analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE174517 | GEO | 2021/10/31

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcriptional changes in HK-2 cells treated with lysophosphatidylcholine (LPC)

Project description:Transcriptional changes in HK-2 cells treated with lysophosphatidylcholine (LPC)

| PRJNA730413 | ENA

LPC-treated mouse skin

Project description:To further understand the molecular mechanism of LPC

2025-02-14 | GSE166832 | GEO

LPC-treated mouse skin

Project description:LPC-treated mouse skin

| PRJNA702098 | ENA

LPC-promoted Th1 differentiation

Project description:To evaluate the gene expression profile via RNA-seq after treatment with LPC under Th1 polarizing conditions.

2025-02-14 | GSE166812 | GEO

Transcriptional profiles LPC-HRas cells with or without ETV4 knockdown

Project description:To determine the molecular signaling pathways responsible for ETV4 regulation of cell growth, RNA sequencing was conducted on LPC-HRas cells with or without ETV4 knockdown

2021-10-30 | GSE184680 | GEO

HK-2 cells: control and Substance P (SP)-treated

Project description:NK-1R axis in HK-2 cells by treated HK-2-overexpressed NK-1R cells with or without SP.

2023-03-20 | GSE216743 | GEO

RNA sequencing of paVICs exposed to LPC and dantrolene

Project description:To investigate the gene expression changes due to LPC-induced calcific nodule formation in porcine aortic valve interstitial cells (paVICs). We then examined differential gene expression due to treatment with dantrolene, which inhibits calcific nodule formation, with and without LPC after 24 hours of exposure.

2023-03-30 | GSE227229 | GEO

LPC-promoted Th1 differentiation

Project description:LPC-promoted Th1 differentiation

| PRJNA702059 | ENA

OPC Cell Culture with LPC 18:1 or LPC 18:1 (both + C13-His)

Project description:Rat OPCs were incubated in the presence of LPC 18:1 or LPC 18:0 and C13-His. Cultures controls included no treatment and a positive control for the differentiation of OPCs. LPC 18:1 was administered at 10 uM while C13-His was administered at 10 uM. Samples were process for mass spectrometry to identify the incorporation of C13-His in newly synthesized proteins.

2022-02-17 | PXD025177 | Pride

Microarray analysis of HK-2 cells treated with cisplatin

Project description:Chemotherapeutic use of cisplatin is limited by its severe side effects. In this study, we demonstrated that cisplatin induces cell death in a proximal tubular cell line by suppressing glycolysis- and tricarboxylic acid (TCA)/mitochondria-related genes. HK-2 cells were cultured to confluence in 100mm dishes. Total RNA was extracted (QIAGEN, Valencia, CA, USA), and the concentration in the samples was measured using a Micro UV-Vis fluorescence spectrophotometer (Malcom, Tokyo, JAPAN). Sample of 10ɥg of Total RNA from HK-2 cells were labeled with biotin (3'IVT Labeling Kit, Affymetrix, USA) and hybridized (GeneAtlas Hybridization, Wash, and Stain Kit for 3' IVT Arrays, Affymetrix). The Microarray platform used was Affymetrix HG U219 Array Strip. The arrays were scanned in a GeneAtlas scanner controlled by GeneAtlas Software (Affymetrix, Sta. Clara, USA). Genes were later filtered according to expression fold change (Affymetrix Expression Console software, Affymetrix) Using Affymetrix GeneAtlas System, we determined the gene expression profiles of HK-2 cells treated with cisplatin. Two replicates were made for each timepoints (control, 6h and 24h).

2015-06-09 | E-GEOD-69644 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data