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Expression data from K5-IKKbeta transgenic mouse skin

ABSTRACT: IKKbeta is a subunit of the IkB kinase (IKK) complex required for NF-kB activation in response to pro-inflammatory signals. NF-kB regulates the expression of many genes involved in inflammation, immunity and apoptosis, and also controls cell proliferation and differentiation in different tissues; however, its function in skin physiopathology remains controversial. We here report the alterations caused by increased IKKbeta activity in basal cells of the skin of transgenic mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE17511 | GEO | 2010/03/22

SECONDARY ACCESSION(S): PRJNA118781

REPOSITORIES: GEO

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Expression data from K5-IKKbeta transgenic mouse skin

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