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ABSTRACT: Determination of how two critical procedural steps in the dSLAM protocol ('diploid synthetic lethality assessed by microarray') affect results Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: ordered

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE1753 | GEO | 2004/11/05

SECONDARY ACCESSION(S): PRJNA90623

REPOSITORIES: GEO

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dSLAM

Project description:These datasets use diploid-based synthetic lethality analysis on microarrays (dSLAM) as a new technology for identifying genetic interactions of various types. These interactions include synthetic lethality (CIN8, BIM1, SGS1), synthetic haploinsufficiency (TUB1), dosage suppression (LCD1), suppression of a lethal mutation (SML1), suppression of an overexpressed conditionally lethal allele (CDC102), and gene-chemical interactions (Benomyl). Keywords = dSLAM yeast heterozygotes barcode tag synthetic lethality suppression Keywords: other

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SML1 synthetic lethality

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Project description:Assessment of growth impairment resulting from a heterozygous tub1 null mutation as compared to that from a heterozygous ura3 null mutation Keywords = TUB1 Keywords = URA3 Keywords = yeast Keywords = deletion Keywords = synthetic haploinsufficiency Keywords = tag Keywords = barcode Keywords: repeat sample

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