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Postprandial effects of protein from salmon by-products and whey on gene expression in liver cells.

ABSTRACT: Exploring the metabolic effects of fish protein is important, as by-products from fish contain large amounts of proteins that could be used for human consumption. The aim of this study was to investigate the postprandial effects of intake of protein from salmon by-products, compared to whey. As part of this effort, the effects on gene expression in liver cells were studied in vitro. This was done by incubating HepG2 cells with human serum taken before (fasting) or 30 and 60 min after intake of salmon protein or whey and comparing that with HepG2 cells incubated in serum-free medium. Transcriptomic profiling of the cells was done with RNA sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE178584 | GEO | 2022/04/12

REPOSITORIES: GEO

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Postprandial effects of protein from salmon by-products and whey on gene expression in liver cells.

Project description:Postprandial effects of protein from salmon by-products and whey on gene expression in liver cells.

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Project description:The present work studies the effect of Debaryomyces hansenii yeast-based products on physiological responses in Atlantic salmon exposed to a short-term stress. For this, a control fishmeal-based diet (CD) and experimental diets containing 0.1% of Debaryomyces hansenii were fed to fish for 8 weeks in fresh water. At the end of the feeding experiment, fish were exposed to 1-minute hypoxia stress and samples were collected post-stress

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