Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Evaluation of bovine milk extracellular vesicles on mouse intestinal gene expression

ABSTRACT: Intestinal tissue samples from dextran sodium sulfate-induced colitis mice were analyzed on their transcriptomic changes using RNA-seq to elucidate the effects of extracellular vesicles pretreatment on the colitis-associated gene expressions.

ORGANISM(S): Mus musculus

PROVIDER: GSE178663 | GEO | 2021/06/23

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Expression data from untreated and DSS-treated Adamts12 WT and KO mice

Project description:Adamts12-deficient mice undergo more severe colitis than WT mice after induction with DSS. We used microarrays to determine the gene expression differences between Adamts12-deficient and WT mice during ulcerative colitis induced with DSS (dextran sodium sulfate)

2012-09-01 | GSE40529 | GEO

Effects of dietary folic acid levles on colitis-associated tumorigenesis.

Project description:Folic acid supplementation (8 mg/kg diet) promotes colon tumor formation in mice with established colitis induced by carcinogen azoxymethane (AOM) and dextran sulfate sodium sulfate (DSS). This induction of colon tumors was associated with hypomethylation of DNA cased by folic acid supplementation.

2023-05-31 | GSE168525 | GEO

Effects of dietary folic acid on methylation status of colon non-neoplastic epithelium and dysplasia in mice with colitis

2023-09-07 | GSE168975 | GEO

Transcriptional profiling of murine distal colon from C57BL/6 (WT) and Stat2KO mice during acute DSS colitis.

Project description:Experimental colitis was induced in mice by the administration of 2% (w/v) Dextran sulfate sodium salt (DSS, colitis grade, 36-50kDa, MP Biomedicals) in the drinking water for 7 days followed by normal drinking water w/o DSS. Distal colons were collected two days later.

2023-10-01 | E-MTAB-12655 | biostudies-arrayexpress

Transcriptional profiling of murine distal colon from C57BL/6 (WT), Il20KO, Il20raKO and Il20rbKO mice during acute DSS colitis

Project description:Experimental colitis was induced in mice by the administration of 1.5% (w/v) Dextran sulfate sodium salt (DSS, colitis grade, 36-50kDa, MP Biomedicals) in the drinking water for 7 days followed by normal drinking water w/o DSS. Distal colons were collected two days later.

2023-10-01 | E-MTAB-12737 | biostudies-arrayexpress

Dextran sodium sulfate treatment of wild type and Pirc rats alters colonic normal tissue gene expression

Project description:Dextran sodium sulfate (DSS) causes inflammation in the gut similar to ulcerative colitis in humans. Patients with ulcerative colitis have increased risk of developing colon cancer. We sought to determine which genes are altered in the normal colonic epithelium, and which changes depend on the Pirc mutation.

2014-01-14 | GSE54005 | GEO

DSS-colitis induced in young age accelerates the onset of cognitive defects in Tg2576 mice, a model of Alzheimer disease

Project description:In this study we explored if colitis induced by dextran sulfate sodium (DSS) in young, presymptomatic/preplaque mice worse and/or anticipate age-dependent cognitive impairment in Tg2576, a widely used mouse model of Alzheimer disease.

2024-05-29 | GSE253108 | GEO

Dextran sodium sulfate treatment of Pirc rats alters colonic and tumor gene expression

Project description:Dextran sodium sulfate (DSS) causes inflammation in the gut similar to ulcerative colitis in humans. Patients with ulcerative colitis have increased risk of developing colon cancer. We sought to determine whether genes altered in the normal colonic epithelium or tumor differed between sporadic and inflammation-associated tumor development.

2014-01-14 | GSE54035 | GEO

GsMTx4 suppresses pro-inflammatory gene expression in DSS-induced colitis in mice.

Project description:The spider venom-derived peptide GsMTx4 specifically inhibits mechanosensory ion channels. It has been reported that GsMTx4 plays an immunoregulatory role in several inflammatory conditions. Therefore, we administrated GsMTx4 to mice with dextran sodium sulfate (DSS)-induced acute colitis, to explore whether it regulates inflammatory responses in colitis.

2023-10-15 | GSE215772 | GEO

The effect of 5-ASA on colitis-associated carcinogenesis

Project description:The impact of the antiinflammatory agent 5-aminosalicylic acid (5-ASA) on the risk for colitis-associated colorectal cancer remains controversial. The chemopreventive activity of 5-ASA was evaluated in the Swiss Webster model of azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colitis-associated neoplasia. Mice were injected with AOM (7.4 mg/kg i.p.) and randomized to receive either vehicle or 5-ASA (75mg/kg) for the remainder of the study. DSS treatment began at 9 weeks of age and continued for 3 cycles. At the time of sacrifice (18 weeks of age), the entire colon and rectum were processed for histopathologic examination and microarray profiling. For information regarding the histopathological analysis, refer to Clapper ML, Gary MA, Coudry RA, Litwin S, Chang WC, Devarajan K, Lubet RA, Cooper HS. 5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis. Inflamm Bowel Dis. 2008 Oct;14(10):1341-7. doi: 10.1002/ibd.20489. PMID: 18452197.

2021-10-10 | GSE185599 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data