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Methylation status in AG- and PG-derived cells and sperm

ABSTRACT: Genomic imprinting describes the expression of a subset of mammalian genes from one parental chromosome. The parent-of-origin specific expression of imprinted genes relies on DNA methylation of CpG-dinucleotides at differentially methylated regions (DMRs) during gametogenesis. We identified the paternally methylated DMRs at mouse chromosome 1 near the imprinted Zdbf2 gene using a methylated-DNA immunoprecipitation-on-chip (meDIP-on-chip) method applied to DNA from parthenogenetic (PG)- and androgenetic (AG)-derived cells and sperm.

ORGANISM(S): Mus musculus

PROVIDER: GSE18126 | GEO | 2010/05/05

SECONDARY ACCESSION(S): PRJNA129043

REPOSITORIES: GEO

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Methylation status in AG- and PG-derived cells and sperm

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