Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Hitoshi Hiura
PROVIDER: E-GEOD-18178 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hiura Hitoshi H Sugawara Atsushi A Ogawa Hidehiko H John Rosalind M RM Miyauchi Naoko N Miyanari Yusuke Y Horiike Tokumasa T Li Yufeng Y Yaegashi Nobuo N Sasaki Hiroyuki H Kono Tomohiro T Arima Takahiro T
Nucleic acids research 20100412 15
The parent-of-origin specific expression of imprinted genes relies on DNA methylation of CpG-dinucleotides at differentially methylated regions (DMRs) during gametogenesis. To date, four paternally methylated DMRs have been identified in screens based on conventional approaches. These DMRs are linked to the imprinted genes H19, Gtl2 (IG-DMR), Rasgrf1 and, most recently, Zdbf2 which encodes zinc finger, DBF-type containing 2. In this study, we applied a novel methylated-DNA immunoprecipitation-on ...[more]