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The prostate cancer androgen receptor cistrome in African American men differs from White men and associates with upregulation of lipid metabolism [AA]

ABSTRACT: We use androgen receptor chromatin immunoprecipitation (AR ChIP) on frozen prostate adenocarcinoma samples and normal prostate counterparts in men of European ancestry as well as men of African (AA) ancestry and derive a model whereby increased androgen signaling drives higher levels of lipogenesis in AA prostate tumors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE181440 | GEO | 2022/06/08

REPOSITORIES: GEO

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The prostate cancer androgen receptor cistrome in African American men differs from White men and associates with upregulation of lipid metabolism [EA]

Project description:We use androgen receptor chromatin immunoprecipitation (AR ChIP) on frozen prostate adenocarcinoma samples and normal prostate counterparts in men of European ancestry as well as men of African (AA) ancestry and derive a model whereby increased androgen signaling drives higher levels of lipogenesis in AA prostate tumors.

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The prostate cancer androgen receptor cistrome in African American men differs from White men and associates with upregulation of lipid metabolism [AA]

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