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Transcriptome-wide effects of NusA on RNA polymerase pausing in Bacillus subtilis

ABSTRACT: In this work we conducted RNET-seq on Wild Type, NusA depletion, nusG deletion, and NusA depletion nusG deletion strains of B. subtilis. Using this data we analysed the transcriptome-wide effects of NusA on RNA polymerase pausing and found that NusA has modest pause stimulating as well as suppressing effects throughout the genome.

ORGANISM(S): Bacillus subtilis

PROVIDER: GSE186285 | GEO | 2021/10/22

REPOSITORIES: GEO

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NusG is an intrinsic transcription termination factor that stimulates motility and cooperatively coordinates global gene expression with NusA

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