Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Regulation of Chromatin Accessibility by hypoxia and HIF_1

ABSTRACT: ATAC-seq was performed to investigate changes in chromatin accessibility in repsonse to hypoxia

ORGANISM(S): Homo sapiens

PROVIDER: GSE186342 | GEO | 2022/03/04

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Regulation of Chromatin Accessibility by hypoxia and HIF_3

Project description:Integrative analysis of RNA-seq with ATAC-seq to investigate changes in chromatin accessibility in repsonse to hypoxia.

2022-03-04 | GSE186370 | GEO

Regulation of Chromatin Accessibility by hypoxia and HIF_2

Project description:ATAC-seq was performed to investigate changes in chromatin accessibility in repsonse to HIF stabilisation via VH298

2022-03-04 | GSE186123 | GEO

Hypoxia-induced transcriptome and chromatin accessibility alterations in mouse cardiac cell line HL-1

Project description:In this study, we performed temporal profiling of transcriptome and chromatin accessibility in HL-1 cells for understanding the molecular mechanisms underlying cardiac responses to hypoxia. We collected HL-1 cells under four conditions (4 h and 8 h of hypoxia exposure, 24 h reoxygenation and the normal condition), applied RNA-seq and ATAC-seq to them and performed pairwise comparison of gene expression and open chromatin status on a genome-wide scale.

2021-12-31 | E-MTAB-8814 | biostudies-arrayexpress

Regulation of chromatin accessibility in hypoxia condition

Project description:Regulation of chromatin accessibility in hypoxia condition

| PRJNA826504 | ENA

Regulation of chromatin accessibility in hypoxia condition

Project description:Hypoxia leads to significant changes at the histone modification marks, including increasing methylation of H3K4, H3K9 and H3K27. However, the overall effect on chromatin accessibility is not fully understood. Here, we employed an ATACseq method on PFA-fixed mouse glioma cell line GL261to test the genomewide chromatin accessibility changes in response to two hypoxic conditions: moderate hypoxia (1% O2) and severe hypoxia (<0.1% O2).

2023-03-05 | GSE200757 | GEO

Regulation of Chromatin Accessibility by hypoxia and HIF_3

Project description:Regulation of Chromatin Accessibility by hypoxia and HIF_3

| PRJNA773654 | ENA

Regulation of Chromatin Accessibility by hypoxia and HIF_2

Project description:Regulation of Chromatin Accessibility by hypoxia and HIF_2

| PRJNA772698 | ENA

Regulation of Chromatin Accessibility by hypoxia and HIF_1

Project description:Regulation of Chromatin Accessibility by hypoxia and HIF_1

| PRJNA773425 | ENA

Chromatin accessibility analysis of primary GCTB samples

Project description:Analysis of chromatin accessibility in primary GCTB samples with ATAC-seq

2020-08-31 | E-MTAB-9512 | biostudies-arrayexpress

Reduced polymerase pausing compensates for increased chromatin accessibility in the aging liver

Project description:Regulation of gene expression is linked to the organization of the genome. With age, chromatin alterations occur on all levels of genome organization, accompanied by changes in the gene expression profile. However, little is known about the changes on the level of transcriptional regulation. Here, we used a multi-omics approach and integrated ATAC-, RNA- and NET-seq to identify age-related changes in the chromatin landscape of murine liver and to investigate how these are linked to transcriptional regulation. We provide the first systematic inventory of the connection between aging, chromatin accessibility and transcriptional regulation in a whole tissue. Aging in murine liver is characterized by an increase in chromatin accessibility at promoter regions, but not in an increase of transcriptional output. Instead, aging is accompanied by a decrease of promoter-proximal pausing of RNA polymerase II (Pol II). We propose that these changes in transcriptional regulation are due to a reduced stability of the pausing complex and may represent a mechanism to compensate for the age-related increase in chromatin accessibility in order to prevent aberrant transcription.

2022-09-15 | PXD034564 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data