Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MRNA sequencing of PBMCs from one THES2 patient and two healthy controls

ABSTRACT: To identify differentially epxressed mRNAs in THES2 patient's PBMCs

ORGANISM(S): Homo sapiens

PROVIDER: GSE186477 | GEO | 2022/03/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

mRNA sequencing of PBMCs from one THES2 patient and two healthy controls

Project description:mRNA sequencing of PBMCs from one THES2 patient and two healthy controls

| PRJNA774045 | ENA

Genome-wide mRNA profiling of PBMCs from TB patients (TB) and healthy controls (HC)

Project description:Transcriptome microarray analysis was conducted to examine the gene expression profiling of PBMCs from active TBs and HCs. All 18,853 mRNAs in the microarray were used to draw a Heatmap of differential genes according to their expression levels. The genes that exhibited significant changes in expression were used for further validation. The TB group (n=15) exhibited a significantly different profile compared to the HC (n=15) group (Fig. 1a). A total of 1,595 differentially expressed mRNAs were identified between the two groups. Of these, 335 mRNAs were up-regulated (fold change ≥ 2), and 1,260 mRNAs were down-regulated (fold change ≥ 2).

2021-11-17 | GSE149458 | GEO

PBMCs from patients with Sjögren's syndrome and healthy controls

Project description:Sjögren's syndrome is an autoimmune disease manifesting primarily as dryness of eyes and mouth. In this study, we compared gene expression in PBMCs between age- and gender-matched patients with Sjögren's syndrome (diagnosed by ACR criteria) and healthy controls. Cells were collected in heparinized tubes and PBMCs were prepared using Ficoll.

2013-09-05 | GSE48378 | GEO

PPD stimulated PBMCs from tuberculosis patients, latent infectious individuals and healthy controls.

Project description:Comprehensively compare the transcriptional difference in PPD stimulated PBMCs from individuals with different tuberculosis infectious status: tuberculosis patients, latent infectious individuals and healthy controls using the microarray analysis. Two-condition experiment, PBMCs vs. PPD-PBMCs. 12 individuals: 4 TB patients, 4 latent infectious individuals and 4 healthy controls.

2012-09-19 | E-GEOD-27984 | biostudies-arrayexpress

PBMCs from patients with SjÃ¶gren's syndrome and healthy controls

Project description:SjÃ¶gren's syndrome is an autoimmune disease manifesting primarily as dryness of eyes and mouth. In this study, we compared gene expression in PBMCs between age- and gender-matched patients with SjÃ¶gren's syndrome (diagnosed by ACR criteria) and healthy controls. Cells were collected in heparinized tubes and PBMCs were prepared using Ficoll. Eleven patients with SjÃ¶gren's syndrome and 16 healthy controls were analyzed for expression of TRIM21, IRF1, IRF2, IRF4 and IRF8.

2013-09-05 | E-GEOD-48378 | biostudies-arrayexpress

Expression profiling of blood from pulmonary tuberculosis patient and healthy controls

Project description:Pulmonary tuberculosis is a multigene disease, and some of the genes affect the development of Pulmonary tuberculosis. The study wants to find different expression genes in blood from Pulmonary tuberculosis patient and normal people who have genetic relationship wtih each other. We used microarrays to detail the global programme of gene expression in the blood between Pulmonary tuberculosis patient's and normal people's who have genetic relationship wtih each other.

2017-12-06 | GSE107731 | GEO

PPD stimulated PBMCs from tuberculosis patients, latent infectious individuals and healthy controls.

2012-09-19 | GSE27984 | GEO

Differentiated expression of ceRNA (circRNA, lncRNA, and mRNA) in PBMCs (peripheral blood mononuclear cells) of healthy controls and AD (atopic dermatitis) patients

Project description:The changed ceRNA expression in PBMCs of healthy controls and AD patients.

2022-06-01 | GSE168694 | GEO

Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls

Project description:Coding and long non-coding RNA metabolism is now revealing its crucial role in Amyotrophic Lateral Sclerosis (ALS) pathogenesis. In this work, we performed Illumina RNA-seq analysis on Peripheral Blood Mononuclear Cells (PBMCs) from Sporadic and mutated ALS patients (mutations in FUS, TARDBP, SOD1, C9Orf72 and VCP genes) and healthy controls. Our aim is the whole-transcriptome characterization of PBMCs content, both in terms of coding and non coding RNAs, in order to compare the disease state to the healthy controls, both for sporadic patients and for mutated patients. Out dataset is a starting point for the omni-comprehensive analysis of coding and long non coding RNAs, from an easy to withdraw, manage and store tissue that shows to be a suitable model for RNA profiling in ALS.

2018-07-04 | GSE115259 | GEO

Human PBMCs: Healthy vs Diabetic nephropathy vs ESRD

Project description:Transcriptional profiling of human PBMCs comparing healthy controls, patients with diabetic nephropathy and patients with ESRD. PBMCs were analyzed as they mediate inflammatory injury. Goal was to determine effects of increasing severity of diabetic nephropathy on global PBMC gene expression. Microarray analysis of PBMCs taken from patients with varying degrees of diabetic nephropathy.

2020-12-01 | GSE142153 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data