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Chromatin isolation by RNA purification sequencing of LINC02015 in human aortic smooth muscle cells

ABSTRACT: This study was designed to explore the role of LINC02015 in regulating biological behaviors of vascular smooth muscle cells (VSMCs) and investigate the interacting targets of LINC02015 with high-throughput techniques and bioinformatics analysis. Chromatin isolation by RNA purification (ChIRP) sequencing was applied to explore the interaction relationship among LncRNA, RNA-binding protein and DNA. Localization of the active binding sites was specified by high-throughput sequencing with STAR2. Peak calling analysis was applied to spot enriched gene peaks with MACS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE188751 | GEO | 2021/11/16

REPOSITORIES: GEO

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