Proteomics

Dataset Information

0

Proteins bound to BTBD7_hsa_circ_0000563 in coronary artery disease


ABSTRACT: We aimed to clarify the possible functional role of hsa_circ_0000563 in coronary artery disease. Therefore, the ChIRP-MS was conducted to explore the interaction between BTBD7_hsa_circ_0000563 and proteins on a genomic scale in human peripheral blood mononuclear cell (PBMC). This project is the raw files of the proteins bound to hsa_circ_0000563 found by ChIRP-MS in PBMC.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Peripheral Blood Mononuclear Cell, Blood

DISEASE(S): Cardiovascular System Disease

SUBMITTER: Enzhi Jia  

LAB HEAD: Enzhi Jia

PROVIDER: PXD033196 | Pride | 2023-03-11

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20210510-ZHX-CON.raw Raw
20210510-ZHX-TREAT.raw Raw
DB_search_psm.csv Csv
checksum.txt Txt
de_novo_only_peptides.csv Csv
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Publications

Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study.

Zhou Hanxiao H   Gan Xiongkang X   He Shu S   Wang Yanjun Y   Zhang Sheng S   Chen Jiaxin J   Zhou Yaqing Y   Hou Can C   Hua Lei L   Zhang Qian Q   Jia Enzhi E  

Clinical proteomics 20221103 1


<h4>Background</h4>BTBD7_hsa_circ_0000563 is a novel circRNA and contains conserved binding sites with RNA-binding proteins. However, BTBD7_hsa_circ_0000563 has not been fully studied in coronary artery disease (CAD). We aimed to clarify the diagnostic value and the possible functional role of BTBD7_hsa_circ_0000563 in CAD.<h4>Methods</h4>A total of 276 human peripheral blood mononuclear cell (PBMC) samples were employed. The circularization of BTBD7_hsa_circ_0000563 was verified via Sanger sequ  ...[more]

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