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Effects of dynamic compressive loading on MSC chondrogenesis

ABSTRACT: Long-term dynamic compression enhanced the mechanical properties of MSC-seeded constructs only when loading was initiated after 21 days of chondrogenic differentiation. This study examined the molecular differences of chondrogenic MSCs compared to undifferentiated MSCs (TGF-beta vs no TGF-beta) and the effects of dynamic loading on MSC chondrogenesis (loading vs free-swelling).

ORGANISM(S): Bos taurus

PROVIDER: GSE18879 | GEO | 2010/11/01

SECONDARY ACCESSION(S): PRJNA121139

REPOSITORIES: GEO

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Effects of dynamic compressive loading on MSC chondrogenesis

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