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Gene expression changes in bone marrow dendritic cell progenitors upon acute and chronic LCMV infection [ATAC-seq_IFNARblockade]

ABSTRACT: IFN-I suppresses the number of pre-pDCs and pDC development after infection, and the mechanisms underlying these changes remain unclear. To address this problem, we investigated the chromatin landscapes of bone marrow DC progenitors from mice infected with lymphocytic choriomeningitis virus (LCMV) after IFN-I receptor blockade with neutralizing antibodies.

ORGANISM(S): Mus musculus

PROVIDER: GSE190437 | GEO | 2024/09/10

REPOSITORIES: GEO

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