MAB21L4 is required for epidermal homeostasis
Ontology highlight
ABSTRACT: RNA-seq was used to define the role of MAB21L4 in epidermal differentiation by first employing CRISPR/Cas9 to disrupt MAB21L4 with two independent single guide RNAs (sgRNAs) to create pools of MAB21L4-ablated primary human keratinocytes that were then placed onto human dermis and grown for three days at the air-liquid interface to generate organotypic skin tissue.
ORGANISM(S): Homo sapiens
PROVIDER: GSE190866 | GEO | 2022/06/24
REPOSITORIES: GEO
ACCESS DATA