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Genome-wide profiling of DNA G-quadruplexes in living neurons

ABSTRACT: We report a genome-wide mapping of DNA G-quadruplexes and histone modifications in living neurons. We used primary cultured neurons from the fetus mouse cortex. Cultured cells were treated with 2 µM Ara-C at DIV3 to prevent the proliferation of mitotic cells and were harvested at DIV10. For iG4 CUT&Tag, a BG4-expressing plasmid was transfected by electroporation at DIV0.

ORGANISM(S): Mus musculus

PROVIDER: GSE191063 | GEO | 2021/12/19

REPOSITORIES: GEO

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