Gene Expression in Human Lung Type II Cells
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ABSTRACT: Normal lung function relies on mature function of alveolar type II cels, which have numerous functions including to regulate ion and fluid flux, produce immune molecules, and synthesize and secrete surfactant to stabilize air spaces. Differentiation of type II cells from precursor epithelial cells is accelerated by exposure of cultured cells to glucocorticoid and cAMP. In these studies we used DNA microarray analysis to identify genes of both fetal and adult type II cells that are regulated by glucocorticoid plus cAMP.
ORGANISM(S): Homo sapiens
PROVIDER: GSE19699 | GEO | 2009/12/30
SECONDARY ACCESSION(S): PRJNA121877
REPOSITORIES: GEO
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